6月28日至29日，台湾国立清华大学脑科学研究中心主任、冷泉港实验室兼职教授江安世博士应邀访问北京生命科学研究所，与部分实验室主任和学生进行了学术交流，并于6月29日下午在研究所做学术报告，报告题目为：Mapping Olfactory Circuits in the Drosophila brain。饶毅博士主持了报告。

摘要：

Neural coding for olfactory sensory stimuli has been mapped near completion in theDrosophila first order center.  How can a fly discriminate two different odors?  We reason that if all connections in the entire olfactory circuitry could be mapped and the excitatory or inhibitory properties for each individual neuron could be determined, the resulting spatial and temporal diagram should allow generation of new hypothesis to explain how the brain computes olfactory signals and elicit appropriate behaviors.  In Drosophila adults, there are approximately 300 projection neurons (PNs) interconnecting between 1300 olfactory sensory neurons (OSNs) and 2500 Kenyon cells (KCs).  To analyze olfactory computation, we begin to construct a pilot platform for archiving three-dimensional images of individual neurons involved in processing olfactory signals from different fly individuals.  Currently, the platform includes a standard mushroom body (MB) averaged both in size and shape from many different fly individuals.  The MB Warping and Affine Registration between standard and reference neuropils allows us to archive individual projection neurons into this common three-dimensional framework.  A pilot database for arbitrary visualization of any selected combinations of PNs and KCs has been generated.